KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CALR
All Species:
58.18
Human Site:
Y182
Identified Species:
85.33
UniProt:
P27797
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27797
NP_004334.1
417
48142
Y182
I
V
R
P
D
N
T
Y
E
V
K
I
D
N
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110217
417
48095
Y182
I
V
R
P
D
N
T
Y
E
V
K
I
D
N
S
Dog
Lupus familis
XP_853393
417
48162
Y182
I
V
R
P
D
N
T
Y
E
V
K
I
D
N
S
Cat
Felis silvestris
Mouse
Mus musculus
P14211
416
47976
Y182
I
V
R
P
D
N
T
Y
E
V
K
I
D
N
S
Rat
Rattus norvegicus
P18418
416
47977
Y182
I
V
R
P
D
N
T
Y
E
V
K
I
D
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514084
419
48477
Y183
I
V
R
P
D
N
T
Y
E
V
K
I
D
N
S
Chicken
Gallus gallus
XP_418262
419
48016
Y195
I
I
R
P
D
Q
T
Y
E
V
K
I
D
N
E
Frog
Xenopus laevis
NP_001080765
413
48503
Y183
I
V
R
P
D
N
T
Y
E
V
K
I
D
N
S
Zebra Danio
Brachydanio rerio
NP_956007
419
48936
Y183
I
V
N
P
D
N
T
Y
E
V
K
I
D
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29413
406
46790
Y182
I
V
R
P
D
N
T
Y
E
V
L
I
D
N
E
Honey Bee
Apis mellifera
XP_392689
403
47156
Y181
I
V
K
P
D
N
T
Y
K
V
L
I
D
N
E
Nematode Worm
Caenorhab. elegans
P27798
395
45598
Y177
I
L
N
S
D
N
T
Y
E
V
K
I
D
G
E
Sea Urchin
Strong. purpuratus
NP_999643
421
48804
Y181
I
V
K
S
D
N
S
Y
E
V
R
I
D
N
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SP22
420
47921
Y188
I
I
R
P
D
A
T
Y
S
I
L
I
D
N
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38858
424
48138
Y185
I
L
R
P
D
A
T
Y
S
I
L
I
D
N
V
Baker's Yeast
Sacchar. cerevisiae
P27825
502
56949
S214
I
I
D
E
S
A
Q
S
F
Q
I
L
I
D
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
94.9
N.A.
94.2
93.7
N.A.
84
59.6
78.1
74.4
N.A.
64.2
66.9
62.5
64.8
Protein Similarity:
100
N.A.
99.7
97.3
N.A.
97.5
97.3
N.A.
92.3
73.9
90.1
85.9
N.A.
76.5
77.6
75.3
79.3
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
80
100
86.6
N.A.
86.6
73.3
66.6
66.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
86.6
100
86.6
N.A.
86.6
86.6
73.3
86.6
Percent
Protein Identity:
N.A.
52.1
N.A.
51.4
26.1
N.A.
Protein Similarity:
N.A.
70
N.A.
68.1
40.8
N.A.
P-Site Identity:
N.A.
60
N.A.
60
6.6
N.A.
P-Site Similarity:
N.A.
73.3
N.A.
73.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
94
0
0
0
0
0
0
0
94
7
0
% D
% Glu:
0
0
0
7
0
0
0
0
75
0
0
0
0
0
38
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
100
19
0
0
0
0
0
0
0
13
7
94
7
0
0
% I
% Lys:
0
0
13
0
0
0
0
0
7
0
63
0
0
0
7
% K
% Leu:
0
13
0
0
0
0
0
0
0
0
25
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
13
0
0
75
0
0
0
0
0
0
0
88
0
% N
% Pro:
0
0
0
82
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
7
0
0
7
0
0
0
0
0
% Q
% Arg:
0
0
69
0
0
0
0
0
0
0
7
0
0
0
0
% R
% Ser:
0
0
0
13
7
0
7
7
13
0
0
0
0
0
44
% S
% Thr:
0
0
0
0
0
0
88
0
0
0
0
0
0
0
0
% T
% Val:
0
69
0
0
0
0
0
0
0
82
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
94
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _